Carboxylic acids and derivatives
=O)NC(=O)OC(C)(C)C | 1g | 525110286](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502424352.JPG-250.jpg)
eMolecules 137130-65-5 | Boc-D-Asp-OMe | Ambeed | MFCD03094776 | 247.247 | C10H17NO6 | 97.000 | COC(=O)[C@@H](CC(O)=O)NC(=O)OC(C)(C)C | 1g | 525110286
Boc-D-Asp-OMe | Ambeed | 137130-65-5 | MFCD03094776 | 247.247 | C10H17NO6 | 97.000 | COC(=O)[C@@H](CC(O)=O)NC(=O)OC(C)(C)C | 1g | 525110286
Medchemexpress LLC ER-27319 (maleate) | 1204480-26-1 | 99.4% | 396.44 | 50 MG
ER-27319 (maleate), an acridone derivative, is a potent and selective SYK inhibitor. It inhibits the tyrosine phosphorylation of SYK and its activity, and can be used for study in allergic diseases. It also inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 μM.
- Potent and selective SYK inhibitor
- Inhibits tyrosine phosphorylation of SYK
- Inhibits release of antigen-induced allergic mediators
- Suitable for study in allergic diseases
Medchemexpress LLC Tos-peg3-ch2cooh | 1581248-63-6 | 100 MG
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs are molecules that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein, facilitating its degradation.
- Utilizes the ubiquitin-proteasome system for selective protein degradation.
- Acts as a linker in the construction of degraders.
Apexbio Technology LLC CAL-101 (Idelalisib, GS-1101) 870281-82-6 100mg
CAL-101 (Idelalisib GS-1101 CAS 870281-82-6) is a selective inhibitor targeting the p110 isoform of phosphatidylinositol 3-kinase (PI3K) an enzyme involved in signaling pathways critical for proliferation and survival of malignant B cells By inhibiting PI3K p110 CAL-101 reduces PI3K-mediated phosphorylation of Akt and other downstream factors leading to enhanced PARP cleavage and caspase activation ultimately inducing apoptosis in malignant B cells CAL-101 has been demonstrated to counteract survival signals initiated by molecules such as CD40 ligand (CD40L) TNF- and fibronectin This agent is valuable in investigating B-cell malignancies
eMolecules 32159-21-0 | Ambeed | (S)-1-((Benzyloxy)carbonyl)-5-oxopyrrolidine-2-carboxylic acid | 25g | 552637506 | A196655 | MFCD00037352 | 263.249 | C13H13NO5
ChemScene | Rubidium Chloride | 5g | 801475410 | CS-0013787 | 7791-11-9 | MFCD00011187 | 120.920 | ClRb
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![eMolecules 53075-09-5 | N,N,N-Trimethyladamantan-1-aminium hydroxide | Ambeed211.349 | C13H25NO | 25.000 | [OH-].C[N+](C)(C)C12CC3CC(CC(C3)C1)C2 | 5g | 552741980](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502424486.JPG-250.jpg)
eMolecules 53075-09-5 | N,N,N-Trimethyladamantan-1-aminium hydroxide | Ambeed211.349 | C13H25NO | 25.000 | [OH-].C[N+](C)(C)C12CC3CC(CC(C3)C1)C2 | 5g | 552741980
N,N,N-Trimethyladamantan-1-aminium hydroxide | Ambeed | 53075-09-5211.349 | C13H25NO | 25.000 | [OH-].C[N+](C)(C)C12CC3CC(CC(C3)C1)C2 | 5g | 552741980
OCc1ccccc1)C(O)=O | 1g | 525043820](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502426134.JPG-250.jpg)
eMolecules 13574-13-5 | Boc-Glu(OBzl)-OH | Ambeed | MFCD00065569 | 337.372 | C17H23NO6 | 97.000 | CC(C)(C)OC(=O)N[C@@H](CCC(=O)OCc1ccccc1)C(O)=O | 1g | 525043820
Boc-Glu(OBzl)-OH | Ambeed | 13574-13-5 | MFCD00065569 | 337.372 | C17H23NO6 | 97.000 | CC(C)(C)OC(=O)N[C@@H](CCC(=O)OCc1ccccc1)C(O)=O | 1g | 525043820
Apexbio Technology LLC CA 074 134448-10-5 25mg
CA 074 (CAS 134448-10-5) is a selective inhibitor of cathepsin B a cysteine protease involved in diverse pathological mechanisms By targeting cathepsin B CA 074 alleviates neurotoxicity induced by amyloid-activated microglia and inhibits proteolytic cascades associated with cell growth suppression and plasminogen activation Additionally CA 074 treatment modulates immune responses by shifting CD4 T cells from a Th2 to a Th1 phenotype reducing IgE and IgG1 levels In vivo studies indicate that CA 074 can attenuate TNF- -induced hepatic injury highlighting its relevance as a research tool in inflammation immunology and neurodegenerative disease investigations
Medchemexpress LLC DIDS sodium salt | 67483-13-0 | 99.1% | 100 MG
DIDS sodium salt is a dual inhibitor of ABCA1 and VDAC1. It also inhibits RAD51, specifically targeting RAD51-mediated homologous pairing and strand exchange reactions. This compound inhibits anion exchange and binding to red blood cell membranes, and can suppress the activation of caspase-3 and -9, making it relevant for cancer research.
- Is a dual inhibitor of ABCA1 and VDAC1.
- Inhibits RAD51.
- Inhibits RAD51-mediated homologous pairing and strand exchange reactions.
- Inhibits anion exchange and binding to red blood cell membranes.
- Inhibits the activation of caspase-3 and -9.
- Can be used in cancer research.